Thursday 26th April 2018

Research findings: fibromyalgia caused by trigger points and successfully treated by trigger point therapy


A scientific research review investigated the link between trigger points (tender lumps that masseurs love to find) and fibromyalgia.  They found that trigger points were an important cause.  Over a period of time chronic pain impulses from trigger points cause a sensitisation of the nervous system.  This results in normal stimuli becoming painful plus a host of other symptoms.  A clinical trial showed that treating trigger points to eliminate these impulses not only diminished localised pain, but also substantially improved overall fibromyalgia symptoms.  The authors not only state that treating trigger points substantially improves fibromyalgia symptoms, they concluded that this approach should be used before any other therapy was initiated.

The evidence

In over 25 years of practice this author has seen countless patients diagnosed as having fibromyalgia.  Every one has had a significant pain from muscles and related tissues, usually involving multiple myofascial trigger points, though some exhibited increased sensitivity, a psychological overlay and various other symptoms symptoms.

A review by in the journal Current Brain and Headache Reports investigated the relationship between fibromyalgia and trigger points, presenting the following evidence.

Trial One

In a trial with 44 patients with fibromyalgia and 50 controls the fibromyalgia patients were found to have on average 10 active (pain producing) and one latent (non pain producing) trigger points.  On the other hand the control group had an average of just 2 latent trigger points.  Furthermore, for the fibromyalgia patients pressing on their trigger points tended to reproduce their fibromyalgia symptoms.

* In research controls are similar people used for comparison purposes.  In this case they were similar except for having no fibromyalgia. 

Trial two

For the diagnosis of fibromyalgia there are 18 (9 symmetrical pairs) of points that are tested for tenderness.  In 30 patients diagnosed with fibromyalgia these tender points were examined both manually and with using surface electrodes for trigger point characteristics. Most were found to be trigger points, and pain from these points reproduced the fibromyalgia symptoms.

Trial three

In a trial of 28 fibromyalgia sufferers subjects were found to have abnormal pain sensitivity to heat on the forearm.  Injections of anaesthetic in trigger points in the muscles  above the shoulders resulted in a reduction in sensitivity to heat.  This demonstrates the core mechanism upon which the sensitisation theory is based.

Trial four

In a double blind trial of 68 fibromyalgia sufferers an injection of anaesthetic into trigger points not only caused a reduction in local and referred pain, but also an improvement in fibromyalgia symptoms overall.  This is a demonstration of the so called “extinguishment of peripheral pain generators treatment”, where simply the cause of the sensitisation is removed.

Trial five

In a controlled trial of 74 fibromyalgia sufferers subjects had trigger points treated with massage and other physical therapy.  They exhibited a reduction in pain and anxiety, and an improvement in sleep.  Improvements were still evident after 6 months.

To quote the conclusion of the reviewers:

“On the whole, the results of the reported studies indicate that nociceptive muscle input in fibromyalgia, most often originate from trigger points, exacerbates fibromyalgia symptoms, and a reduction/extinction of this input substantially contributes to improving the fibromyalgia condition. …  Thus, a systematic search for trigger points in fibromyalgia and their extinction is an approach that should systematically be adopted before any other therapy is initiated when faced with a patient with fibromyalgia.”

A clinical perspective

This research explains what musculoskeletal practitioners have been seeing in practice for a very long time. People diagnosed with fibromyalgia usually have a great number of trigger points, and the treatment of trigger points helps. Science provides the mechanism that explains this. Trigger points bombard the nervous system with pain signals until the nervous system becomes sensitised, resulting in normal stimuli becoming painful and painful stimuli being highly exaggerated. The treatment of trigger points removes this constant bombardment allowing the nervous system to recover. This situation is often allowed to develop because trigger points do not show up in scans or medical tests, are not treated by drugs or surgery, and therefore are overlooked or not considered in the diagnosis and management of those with pain. The following comments on the treatment of trigger pointgs are based on 25+ years of clinical practice and the reading of other research.

Trigger points are tough

It is easy for researchers to do something such as inject trigger points with anaesthetic to temporarily extinguish their pain impulses and measure the results.  However, as discussed elsewhere, in practice the extinguishment of trigger points is a long time consuming process.  In trial five the researchers used therapies over 20 weeks.  When additional sensitivity is a factor, such as in fibromyalgia, a larger number of smaller applications of therapy may be appropriate.  Our massagers are designed for home use under professional advice, making this more practical and affordable.

Prevention is better than a cure

The researchers failed to state the obvious.  The chronic pain impulses from muscles and related tissues causes a sensitisation of the nervous system resulting in fibromyalgia.  Wouldn’t it be easier to deal with muscular and related  issues appropriately, have regular massages, trigger point screening and so forth so people would net get the chronic pain then fibromyalgia would not develop.  Again, our massager were designed to help make this more practical and affordable.


Giamberardino MA, Affaitati G, Fabrizio A, Costantini R Effects of treatment of myofascial trigger points on the pain of fibromyalgia. Curr Pain Headache Rep. 2011 Oct;15(5):393-9

Professional consultation

We do not encourage people to self diagnose and self treat fibromyalgia. However, fibromyalgia is still largely considered as a condition with an unknown cause and treated symptomatically with things like anti-depressant drugs. As discussed, trigger points are often not considered. We encourage you to share this information with your health care professional. Download the .pdf of the practitioner version of this summary: Download

Future articles and sharing

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About Dr Graeme

Several years ago Dr Graeme, a Chiropractor practicing in Victoria, Australia was looking for a serious hand held massager his patients could use at home to get the extra quality massage they needed. The ones he found in the shops and on-line for home use looked nice but were not serious, and ... read more