Appendix One: results in the scientist's own words
The following is a direct summary from the trial testing the effects of vibration on the healing of injured nerves. There are a few technical terms, but overall it's pretty easy to understand (13).
Effect of Mechanical Massage Treatment on Muscles of Limbs
Mechanical vibration massage treatment has obvious effect on muscular atrophy induced by nerve root injury. It can dilate capillary, increase volume of blood flow, so as to greatly improve blood supply and nutrition in local tissue; It can make the wall of micrangium rhythmically flatten and restore, accelerating flow of blood; And it can promote contraction and extension of muscle fibers, strengthen muscular tension, elasticity and tolerance, so, it can prevent and cure muscular atrophy.
Effect of Mechanical Massage on Secretion of NGF (Nerve Growth Factor- a growth hormone)
Benign stimulation of mechanical vibration massage can activate the response of nerve immune and neuroendocrine systems, and transmit the signals to the submandibular gland through complicated ways, promoting secretion and storage of NGF in the submandibular gland. Finally, NGF is transported to brachial plexus root injury area through digestive, circulative and nerve systems.
Effect of Mechanical Massage on Repair of Injured Nerves
Mechanical vibration massage can effectively promote the repair of myelin sheath and axes of injured brachial plexus in the rat. It can effectively improve blood circulation of the injured myelin sheath, promote proliferation of SC and survival of the cell body of injured neurons, so as to form a necessary regenerative micro-environment early for repair of nerve, and it induces stress responses of immune and neuroendocrine systems in the rat,promotes secretion of NGF in this gland, and it can improve peripheral nerve units and excite peripheral nerves, so as to accelerate their conduction reflection.
Effect of Mechanical Massage on Na+, K+-ATPase Activities
Na+, K+-ATPase activity on the surface of muscular cell membrane is an important limited factor for excitability and contractile strength of muscular cells. After skeletal muscles lose nervous innervation, generation of ATP is hindered, so Na+, K+-ATPase activity decreases. Under the mechanical massage stimulation, the muscular cells cultured in vitro show increases in stress-related gene expression and protein synthesis, leading to adaptability reconstruction of structures and contractile characters of the muscular cells, which are closely related with activation of Na+, K+-ATPase, and influences the distribution and functional activity of Na+, K+- ATPase on the surface of muscular cell membrane. In brief, mechanical vibration massage can promote the regeneration and recovery of the brachial plexus, and effectively slow down the decrease of Na+, K+-ATPase activities induced by the nerve injury, preventing muscular atrophy, and it promotes the generation of submandibular gland NGF, providing a favorable environment for regeneration of nerve"